Relationship between Length of Sleep and Oxidative Stress Marker, Urinary 8-Hydroxy-2'-Deoxyguanosine
نویسندگان
چکیده
منابع مشابه
[Relationship between length of sleep and oxidative stress marker, urinary 8-hydroxy-2'-deoxyguanosine].
OBJECTIVES In this study, we aim to examine whether the length of sleep modifies the level of urinary 8-hydroxy-2'-deoxyguanosine (8-OH-dG). METHODS Subjects were 146 workers who were engaged in management, clerical work, laboratory work, or business at a certain company. We obtained information on the subjects concerning gender, body mass index, drinking and smoking habits, and the lengths o...
متن کاملUrinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage.
DNA is subject to constant oxidative damage from endogenous oxidants. The oxidized DNA is continuously repaired and the oxidized bases are excreted in the urine. A simple routine analytical procedure is described for urinary 8-hydroxy-2'-deoxyguanosine, an oxidative DNA damage adduct, as an indicator of oxidative damage in humans and rodents. This adduct was purified from human urine and charac...
متن کاملUrinary Sulfate, Asymmetric Dimethylarginine, and 8-Hydroxy-2'-Deoxyguanosine:
Compounds found in the urine represent the end products of metabolism and are the expression of the efficiencies or inefficiencies of this process. Nutritional status has a direct effect on this metabolic efficiency. Careful assessment of certain urinary compounds can yield valuable information on the nutrient needs of the individual. Urinary sulfate, asymmetric dimethylarginine (ADMA), and 8-h...
متن کاملHelicobacter pylon Infection and Urinary Excretion of 8-Hydroxy-2- deoxyguanosine, an Oxidative DNA Adduct1
To assess whether Helicobacter pylon-related inflammation increases oxidative DNA damage, we evaluated the association between H. pylon infection and urinary excretion of an adduct of oxidative DNA damage, 8-hydroxy-2-deoxyguanosine (8ohdG). Subjects included 555 healthy persons, ages 20-39, within the Kaiser Permanente Medical Care Program in Northern California. We tested sera for antibodies ...
متن کامل8-hydroxy-2′-deoxyguanosine in colorectal adenocarcinoma – is it a result of oxidative stress?
BACKGROUND 8-hydroxy-2'-deoxyguanosine (8-OHdG) is one of the most abundant oxidatively modified lesions in DNA and is a marker of the oxidative stress. 8-OHdG is a mutagenic lesion and it can mispair with adenine, causing G:C→T: A transversion. Our task was to determine the 8-OHdG level in patients with colorectal adenocarcinoma directly in tumor tissues and corresponding normal mucosa. MATE...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)
سال: 2006
ISSN: 0021-5082,1882-6482
DOI: 10.1265/jjh.61.357